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If any part of that process is compromised—whether from your diet, a medical issue, or just the natural effects of aging—a deficiency can set in

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In a similar study, the pivotal role for the IGF-1 in insulin sensitivity has received further support from liver-specific IGF-1 KO mice which exhibited overt insulin resistance and hyperinsulinaemia that was reversed by the administration of IGF-1 [161]

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