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To confirm the importance of RFK and FLAD1 in FSP1 regulation, we generated RFK -KO and FLAD1 -KO cells (RFK KO and FLAD1 KO cells) in the FSP1 GFP-P2A-BFP cell line
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Small sample size, insufficient sequencing depth, possible contamination in the experimental process, and various factors affecting the microbial composition of feces, such as diet, in addition to a lack of quantitative definition, make the results unreliable, and better methods remain to be explored to provide access to the relationship between psoriasis and strain-level intestinal bacteria so that psoriasis can be diagnosed and treated with microbial interventions
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