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Melanogenesis and Its Biological Significance Melanogenesis is a fundamental physiological process responsible for generating melanin pigments that determine cutaneous and hair pigmentation while supporting epidermal homeostasis

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Cell isolation Skin fragments were collected during routine surgical procedures and placed in phosphate buffered saline (PBS) (Sigma Aldrich) with 100 units/ ml penicillin and 100 µg/ml streptomycin solution (P/S) (Sigma Aldrich)